Endocrine Abstracts

Insulin pump is one of the treatment options for patients with type 1 diabetes mellitus. In July 2008, NICE has issued Technological Appraisal (TA 151) regarding insulin pump therapy guidance.Objective of the audit: To measure current practice in Colchester General Hospital in continuous subcutaneous insulin infusion – CSII (insulin pump) for the treatment of diabetes mellitus against the recommendations in the technological appraisal (TA 151).<...

A 52-years man was admitted following a Road Traffic Accident.He was a known smoker but usually fit and well. During the road traffic accident he sustained fracture of all four limbs, clavicles, facial bones as well as multiple rib fractures.Following initial stabilisation in ITU he underwent multiple orthopaedic surgeries for his bony fractures over the next 2–3 months.He was then noticed to have elevat...

A 48-year man, referred with symptoms suggestive of phaeochromocytoma and elevated 24 h urinary noradrenalin level. He had a background history of obstructive sleep apnoea, controlled hypertension and obesity. His medications included Amlodipine 10 mg od, Modafinil 200 mg daily, Amitriptyline 10 mg and Rabeprazole.Obstructive sleep apnoea was diagnosed at 39 years. CPAP was tried and later Modafinil 100 mg daily. A few months prior to referral his Modafi...

Summary: A case of intermittent hypercalcemia with a suppressed parathyroid hormone (PTH) for nearly 3 years. It was found that high calcium specifically occurred in summer and each one lasted for about a month. Once calcium normalised the renal function also improved. Exact aetiology has not been found even after extensive investigations.Case presentation: A 67-year-old gentleman first presented to the endocrine clinic in early 2014 with Hypercalcemia. ...

We set out to describe a case of persistent PTH elevation post parathyroid carcinoma resection and assess its significance via literature review. A 71 year old lady presented with abdominal pain and weight loss. Blood tests revealed calcium of 3.42 mmol/l and PTH of 47.8 pmol/l. Ultrasound neck and SESTAMIBI scan suggested right lower parathyroid adenoma. She underwent right inferior parathyroidectomy however histology revealed parathyroid carcinoma with incomplete excision ne...

Introduction: Abiraterone acetate, potent selective irreversible inhibitor of CYP17A1, is increasingly used with prednisone to treat prostate cancer resistant to androgen deprivation therapy.Case Presentation: 64-year-old gentleman with BG of prostate cancer with widespread metastatic bone disease. He was on abiraterone since 2019. Admitted with generally unwell, aches/pains, headache, and dizziness. Euvolemic hyponatrem...